Though I don’t recommend this but sometimes we require to move Thunderbird profiles. Follow below steps to do that:
a) Shut down Thunderbird.
b) Move the profile folder to the desired location.
c) Open up the profiles.ini file in a text editor. you can find the file location in the application data folder for Thunderbird:
The path is %AppData%\Thunderbird\ for Windows.
d) In the profiles.ini file, locate the entry for the profile you’ve just moved. Change the Path= line to the new location.
If you switch from a relative path to a non-relative path, the direction of the slashes may need to change. For example, in Windows, non-relative paths use backslashes, whereas relative ones use forward slashes.
e) Change IsRelative=1 to IsRelative=0.
f) Save profiles.ini and restart Thunderbird.
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